DOTA-2P (FAPI) 2

• Description:

  DOTA-2P (FAPI) 2 is a dimeric FAP (fibroblast activation protein) that can be used as a PET imaging agent and a tracer for tumor therapy[1].

• UNSPSC:

  12352005

• Target:

  FAP

• Related Pathways:

  Immunology/Inflammation

• Field of Research:

  Cancer

• Smiles:

  O=C(C1=CC=NC(C=C2)=C1C=C2N(C)CCCN(CC3)CCN3C(COCCOCCOCCNC(CCC(N[C@@H](CCCCNC(CN(CCN(CC4)CC(O)=O)CCN(CCN4CC(O)=O)CC(O)=O)=O)C(NCCOCCOCCOCC(N5CCN(CCCN(C)C(C=C6)=CC7=C6N=CC=C7C(NCC(N8CC(F)(F)C[C@H]8C#N)=O)=O)CC5)=O)=O)=O)=O)=O)NCC(N(CC9(F)F)[C@@H](C9)C#N)=O

• Molecular Formula:

  C92H132F4N22O22

• Molecular Weight:

  1974.16

• References & Citations:

  [1]Zhao L, Niu B, Fang J, et al. Synthesis, Preclinical Evaluation, and a Pilot Clinical PET Imaging Study of 68Ga-Labeled FAPI Dimer. J Nucl Med. 2022;63 (6) :862-868.|[2]Zhao L, et al. Synthesis, Preclinical Evaluation, and a Pilot Clinical PET Imaging Study of 68Ga-Labeled FAPI Dimer. J Nucl Med. 2022 Jun;63 (6) :862-868.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported