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HBpep-SA (TFA)

CAT: 0804-HY-P6020A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P6020A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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UNSPSC Description
HBpep-SA is a cell membrane-permeable peptide condensate that phase separates to form stable droplets at pH values below 6.5. HBpep-SA is able to directly and efficiently deliver a variety of macromolecules, ranging from therapeutic peptides as small as 726 Da to large enzymes as large as 430 kDa, and the loaded condensates remain stable under near-physiological and serum conditions until internalized by cells. HBpep-SA can be used for intracellular delivery of large numbers of macromolecules and as a vector for mRNA-based vaccines[1].
Target Antigen
Others
Type
Peptides
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/hbpep-sa-tfa.html
Purity
98.76
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
O=C(OCCSSCCOC(C)=O)NCCCC[C@H](NC([C@@H](NC([C@H]1N(CCC1)C(CNC([C@@H](NC(CNC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(CNC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(CN)=O)CC2=CNC=N2)=O)=O)C(C)C)=O)CC3=CC=C(O)C=C3)=O)=O)CC4=CNC=N4)=O)=O)C(C)C)=O)CC5=CC=C(O)C=C5)=O)=O)CC6=CNC=N6)=O)=O)=O)CC7=CC=C(O)C=C7)=O)C(NCC(N[C@H](C(NCC(N8[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CC9=CNC%10=CC=CC=C9%10)=O)CC%11=CC=C(O)C=C%11)=O)CC(C)C)=O)=O)CC%12=CNC=N%12)=O)=O)CC%13=CC=C(O)C=C%13)=O)CCC8)=O)=O)CC%14=CNC=N%14)=O)=O.OC(C(F)(F)F)=O.[x]
Molecular Weight
3132.41 (free base)
References & Citations
[1]Sun Y, et al. Phase-separating peptides for direct cytosolic delivery and redox-activated release of macromolecular therapeutics. Nat Chem. 2022 Mar;14(3):274-283.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Clinical Information
No Development Reported

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