Donitriptan (mesylate)

CAT: 0804-HY-106157ASize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-106157ASize:1 Each
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Description
Donitriptan Mesylate is a potent, high efficacy agonist at 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively[1].
CAS Number
[200615-15-2]
Product Name Alternative
F-11356 (mesylate)
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/donitriptan-mesylate.html
Solubility
10 mM in DMSO
Smiles
CS(=O)(O)=O.NCCC1=CNC2=C1C=C(OCC(N3CCN(C4=CC=C(C#N)C=C4)CC3)=O)C=C2
Molecular Formula
C24H29N5O5S
Molecular Weight
499.58
References & Citations
[1]Muñoz-Islas E, et al. Donitriptan, but not sumatriptan, inhibits capsaicin-induced canine external carotid vasodilatation via 5-HT1B rather than 5-HT1D receptors. Br J Pharmacol. 2006 Sep;149 (1) :82-91.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor

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