FBPase-IN-4

• Description :

  FBPase-IN-4 (Compound 11 n) is a potent FBPase (Fructose-1,6-bisphosphatase) inhibitor with a Ki value of 1.78 μM. FBPase-IN-4 can be used in type 2 diabetes research[1].

• UNSPSC :

  12352211

• Target :

  FBPase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/fbpase-in-4.html

• Smiles :

  BrCC(NCCC1=CC=C(S(=O)(NC(NC2=CC=C(C3=CC=CC=C3)C=C2)=O)=O)C=C1)=O

• Molecular Formula :

  C23H22BrN3O4S

• Molecular Weight :

  516.41

• References & Citations :

  [1]Cao H, et al. Structure-Guided Design of Affinity/Covalent-Bond Dual-Driven Inhibitors Targeting the AMP Site of FBPase. J Med Chem. 2024 Nov 28;67 (22) :20421-20437.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported