FBPase-IN-3

• UNSPSC Description:

  FBPase-IN-3 (compound 45) is a FBPase (fructose-1,6-bisphosphatase) inhibitor with an IC50 of 2.08 μM. FBPase-IN-3 exhibits potent inhibitory activity of gluconeogenesis[1].

• Target Antigen:

  FBPase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/fbpase-in-3.html

• Smiles:

  O=C(NS(=O)(C1=CC=C(OC)C=C1)=O)C2=CC(Cl)=CC(C3=NC4=CC=CC=C4N3)=C2

• Molecular Weight:

  441.89

• References & Citations:

  [1]Huahao Wang, et al. Discovery of novel fructose-1,6-bisphosphatase inhibitors bearing benzimidazole scaffold using a dual-ligand molecular docking model. Eur J Med Chem. 2024 Sep 19:279:116888.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported