Products for Research Use Only
RegisterLogin

ACADM Antibody / Mcad

CAT: 0800-RQ6916Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-RQ6916Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ACADM (acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain) is a gene that provides instructions for making an enzyme called acyl-coenzyme A dehydrogenase that is important for breaking down (degrading) a certain group of fats called medium-chain fatty acids. This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence: 5 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P11310
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant human ACADM/MCAD protein (amino acids S38-E401) was used as the immunogen for the ACADM antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, FACS, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the ACADM antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This ACADM antibody is available for research use only.
Storage Conditions
After reconstitution, the ACADM antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the ACADM antibody should be determined by the researcher.
Image Legend
Immunofluorescent staining of FFPE human HeLa cells with ACADM antibody (green) and DAPI nuclear stain (blue) . HIER: steam section in pH6 citrate buffer for 20 min.

UniProtKB · P11310

Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

ACADM_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P11310
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ACADM
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
MCAD
EC number
1.3.8.7
Processing
Precursor
Secondary accessions
Q5T4U4, Q9NYF1
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Disease

Disease variant

Ligand

FADFlavoprotein

Biological process

Fatty acid metabolismLipid metabolism

Cellular component

Mitochondrion

Molecular function

Oxidoreductase

Domain

Transit peptide

Related Products

CatalogName
RQ5361Mcad Antibody / ACADM
RZ1138Zebrafish Mcad Antibody / Acadm
F42746-0.08MLACADL Antibody
F51188-0.08MLACADL Antibody
F51188-0.4MLACADL Antibody
F42746-0.4MLACADL Antibody
RQ7449ACAD9 Antibody
RQ5790ACADS Antibody / SCAD
R31643MCAK Antibody
V4672-100UGKIF2C Antibody / MCAK

Alternative Products

CatalogName
MBS2401320-01Anti-MCAD/ACADM Antibody
A02383Anti-MCAD ACADM Antibody
APR08372GPolyclonal MCAD / ACADM Antibody
C20053-50uLACADM/MCAD Antibody [P2N1]
MBS1755076-01Anti-ACADM/MCAD Antibody Picoband
GTR17691864ACADM/Mcad Rabbit Monoclonal Antibody
A02383-3Anti-ACADM/MCAD Antibody Picoband®
GTR17694739ACADM/MCAD Rabbit Polyclonal Antibody
GTR18759225ACADM/MCAD Rabbit Polyclonal Antibody (Fluoro488)
GTR18759218ACADM/MCAD Rabbit Polyclonal Antibody (Fluoro550)

Popular Products