Products for Research Use Only
RegisterLogin

MCAK Antibody

CAT: 0800-R31643Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-R31643Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Kinesin-like protein, also called Mitotic centromere associated kinesin (MCAK), is a protein that in humans is encoded by the KIF2C gene. It is mapped to 1p34.1. The protein encoded by this gene is a member of kinesin-like protein family. Most proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein acts to regulate microtubule dynamics in cells and is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation. MCAK uses microtubule depolymerizing activity to correct improper microtubule attachments at kinetochores.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 0.5-1 µg/mL, Immunofluorescence (FFPE) : 2-4 µg/mL, Flow cytometry: 1-3ug/million cells
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Human partial recombinant protein (AA 531-725) was used as the immunogen for this MCAK antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, FACS
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the MCAK antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This MCAK antibody is available for research use only.
Storage Conditions
After reconstitution, the MCAK antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the MCAK antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Immunofluorescent staining of FFPE human U-2 OS cells with MCAK antibody (green) and DAPI nuclear stain (blue) . HIER: steam section in pH6 citrate buffer for 20 min.

Related Products

CatalogName
V4672-100UGKIF2C Antibody / MCAK
V4672SAF-100UGKIF2C Antibody / MCAK
V4671-20UGKIF2C Antibody / MCAK
V4672-20UGKIF2C Antibody / MCAK
V4671SAF-100UGKIF2C Antibody / MCAK
V4671-100UGKIF2C Antibody / MCAK
V4676SAF-100UGKIF2C Antibody / Kinesin Family Member 2C / MCAK
V4692-100UGKinesin Family Member 2C Antibody / KIF2C / MCAK
V4684SAF-100UGKIF2C Antibody / Kinesin family member 2C / MCAK
V4692SAF-100UGKinesin Family Member 2C Antibody / KIF2C / MCAK

Alternative Products

CatalogName
70R-12061MCAK antibody
MBS177491-01Anti-MCAK Antibody
RC-7031-01Recombinant MCAK Antibody
APR17332GPolyclonal MCAK Antibody
GTR18219892-01Rabbit MCAK Antibody
MB12114MCAK monoclonal antibody
GTR18298172-01MCAK monoclonal antibody
GTR17695520MCAK Rabbit Monoclonal Antibody
GTR18334439-01MCAK Rabbit mAb Antibody
GTR18213881-01Rabbit MCAK IHC Antibody

Popular Products