PIM2 Assay Kit

• Background :

  PIM kinases (PIM1, PIM2 and PIM3) are a family of serine/threonine protein kinases that play crucial roles in cell survival, proliferation, and drug resistance. PIM kinases are overexpressed in several tumors and promote growth and survival of malignant cells through cell cycle regulation and/or inhibition of apoptosis. Recently, PIM kinases were identified as a potential therapeutic target for precision medicine of advanced cancer.

• Description :

  The PIM2 Assay Kit is designed to measure PIM2 activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent.Need us to run inhibitor screens or profile your compounds against PIM2? Check out ourKinase Screening Services.

• UniProt :

  Q9P1W9

• Format :

  CatalogNumberReagentAmountStorage40153PIM22.5 µg-80°CAvoidmultiplefreeze/thawcycles!793345x Kinase assay buffer1.5 ml-20°C79686ATP (500 μM) 100 µl-20°C79884PIM substrate (S6Ktide, 10 mg/ml) 100 µl-20°C7969696-well plate, white1Room Temp.

• Shipping Conditions :

  -80°C

• Storage Conditions :

  Up to 6 months when stored as recommended.