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GSK3α Assay Kit

CAT: 0421-79698Size: 96 ReactionsDry Ice: YesHazardous: No
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CAT#:0421-79698Size:96 Reactions
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GSK3 (Glycogen synthase kinase) is a serine/threonine kinase which initially was found to phosphorylate and inactivate glycogen synthase in glycogen biosynthesis. It is an important regulator enzyme in many disease pathogeneses including cancer, immune disorders, metabolic disorders and neurological disorders like Alzheimer’s disease. Recently, GSK3α, one of the isoforms of GSK3, was identified as a key target in acute myeloid leukemia (AML) .
Description
The GSK3α Assay Kit is designed to measure GSK3α activity for screening and profiling applications using Kinase-Glo® (Promega) as a detection reagent.Need us to run inhibitor screens or profile your compounds against GSK3α? Check out ourKinase Screening Services.
UniProt
P49840
Format
CatalogNumberComponentsAmountStorage40006GSK3α*1.5 µg-80°CAvoidfreeze/thawcycles!793345x Kinase assay buffer1.5 ml-20°C79686ATP (500 µM) 100 µl-20°C796971 mg/ml GSK substrate peptide500 µl-20°C7969696-well plate, white1Room Temp.*The concentration of GSK3α is lot-specific and will be indicated on the tube containing the enzyme.
Shipping Conditions
-80°C
Storage Conditions
Up to 6 months when stored as recommended.
Contraindications
Keep final DMSO concentration below 1%

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