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TrkA Assay Kit

CAT: 0421-79548Size: 96 ReactionsDry Ice: YesHazardous: No
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CAT#:0421-79548Size:96 Reactions
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The tropomyosin receptor kinases (TRK) are a family of tyrosine receptor kinases, which include TrkA, TrkB and TrkC. TrkA is activated by binding to nerve growth factor (NGF), resulting in activation of cell proliferation through the RAS/MAPK/ERK and PLCγ/PI3K pathways. Constitutive activation of TrkA is associated with colorectal cancer, suggesting TrkA inhibitors may have potential therapeutic value. The TrkA Assay Kit is designed to measure TrkA activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent.Need us to run inhibitor screens or profile your compounds against TrkA? Check out ourKinase Screening Services.
UniProt
P04629
Format
Catalog #ReagentAmountStorage40280TrkA10 µg-80°CAvoidmultiplefreeze/thawcycles!793345x Kinase assay buffer 11.5 ml-20°C79686ATP (500 µM) 100 µl-20°C40217PTK substrate Poly (Glu: Tyr 4:1) (10 mg/ml) 100 µl-20°C7969696-well plate, white1Room Temp
Shipping Conditions
-80°C
Storage Conditions
Up to 6 months when stored as recommended

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