CD38 (Pig) Fluorogenic Assay Kit (Hydrolase Activity)

• Background :

  CD38, a differentiation antigen of B lymphocytes, is a type II integral membrane protein that functions as an ADP-ribosyl cyclase and nicotinamide adenine dinucleotide (NAD) glycohydrolase. The main enzymatic activity of CD38 is the hydrolysis of NAD. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in various cells, including pancreatic ß cells. CD38 is a prognostic biomarker for acute B lymphoblastic leukemia.

• Description :

  The Pig CD38 Inhibitor Screening Assay Kit (Hydrolase Activity) is designed to measure the glycohydrolase activity of porcine CD38 for screening and profiling applications. In addition, the kit includes the CD38 inhibitor apigenin for use as a control inhibitor.Need us to run inhibitor screens or profile your compounds against CD38 (Pig) (Hydrolase Activity) ? Check out ourImmunotherapy Biochemical Screening Services.

• UniProt :

  F1S5D9

• Applications :

  Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.

• Format :

  CatalogNameAmountStorage101019CD38 (Pig) 25 μg-80°C4x CD38 hydrolase buffer4 ml-20°CCD38 substrate (ε-NAD) 200 μl-20°CApigenin (50 mM in DMSO) 10 μl-20°C79685Black 96-well plate1RoomTempPlate sealing film2RoomTemp

• Shipping Conditions :

  -80°C

• Storage Conditions :

  This assay kit will perform optimally for up to 6 months from date of receipt when the materials are stored as directed.

• Notes :

  Trouble Shooting GuideVisitbpsbioscience.com/assay-kits-faqfor detailed troubleshooting instructions. For all further questions, please email[email protected]