ITK ligand 1

• UNSPSC Description:

  ITK ligand 1 is a PROTAC target protein ligand (Ligand for Target Protein for PROTAC). ITK ligand 1 can be used in the synthesis of PROTACs (e.g. HY-149917)[1].

• Target Antigen:

  Itk; Ligands for Target Protein for PROTAC

• Type:

  Reference compound

• Related Pathways:

  PROTAC;Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/itk-ligand-1.html

• Smiles:

  O=C(NC1=CN([C@@H](CCCl)C2=CC=CC=C2)N=C1)C3=NNC4=C3CCC(C)(C)C4

• Molecular Weight:

  411.93

• References & Citations:

  [1]Zhou, et al. Discovery of Potent and Highly Selective Interleukin-2-Inducible T-Cell Kinase Degraders with In Vivo Activity. Journal of medicinal chemistry. 2023, 66(7), 4979–4998.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported