RasGRP3 ligand 1

• UNSPSC Description:

  RasGRP3 ligand 1 (compound 96) is a RasGRP3 ligand with a Ki of 1.75 nM. RasGRP3 ligand 1 can induce Ras activation and can be used for cancer research[1].

• Target Antigen:

  Ras

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;MAPK/ERK Pathway

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/rasgrp3-ligand-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CN1C2=CC=CC=C2C(/C=C3CC(CO)(OC\3=O)COC(C(C)(C)C)=O)=C1

• Molecular Weight:

  371.43

• References & Citations:

  [1]Ann J, et al. α-Arylidene Diacylglycerol-Lactones (DAG-Lactones) as Selective Ras Guanine-Releasing Protein 3 (RasGRP3) Ligands. J Med Chem. 2018 Jul 26;61(14):6261-6276.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2229068-13-5