β2AR ligand 1

• Description:

  β2AR ligand 1 (Compound 4) is a homobivalent bitopic ligand for β2 adrenergic receptor (β2AR) on the orthosteric binding site (OBS) and the metastable binding sites (MBS) [1].

• UNSPSC:

  12352211

• Target:

  Adrenergic Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/β2ar-ligand-1.html

• Smiles:

  C=CCC1=C(C=CC=C1)OC[C@H](CNCCCC2=CN(N=N2)CCCCC3=CC=C(C=C3)OC[C@H](CNC(C)C)O)O

• Molecular Formula:

  C33H49N5O4

• Molecular Weight:

  579.77

• References & Citations:

  [1]Gaiser BI, et al., Bitopic Ligands Support the Presence of a Metastable Binding Site at the β2 Adrenergic Receptor. J Med Chem. 2024 Jul 11;67 (13) :11053-11068.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [3051498-44-0]