β2AR ligand 1

• Description :

  β2AR ligand 1 (Compound 4) is a homobivalent bitopic ligand for β2 adrenergic receptor (β2AR) on the orthosteric binding site (OBS) and the metastable binding sites (MBS) [1].

• UNSPSC :

  12352211

• Target :

  Adrenergic Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/β2ar-ligand-1.html

• Smiles :

  C=CCC1=C(C=CC=C1)OC[C@H](CNCCCC2=CN(N=N2)CCCCC3=CC=C(C=C3)OC[C@H](CNC(C)C)O)O

• Molecular Formula :

  C33H49N5O4

• Molecular Weight :

  579.77

• References & Citations :

  [1]Gaiser BI, et al., Bitopic Ligands Support the Presence of a Metastable Binding Site at the β2 Adrenergic Receptor. J Med Chem. 2024 Jul 11;67 (13) :11053-11068.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [3051498-44-0]