GITR Antibody / TNFRSF18

GITR Antibody / TNFRSF18

• Description: The tumor necrosis factor receptor (TNFR) superfamily represents a growing family of type I transmembrane glycoproteins that are involved in various cellular functions, including proliferation, differentiation and programmed cell death. These proteins share homology for cysteine-rich repeats in the extracellular ligand binding domain and an intracellular death domain. Members of the TNFR superfamily transmit signals through protein-protein interactions, and these signals can lead to the activation of either the caspase and Jun kinase pathways, which promote cell death, or the NFB signaling pathway.
• CAS Number: 9007-83-4
• UniProt: Q9Y5U5
• Host: Mouse
• Immunogen: Human full-length TNFRSF18 protein was used as the immunogen for this TNFRSF18 antibody.
• Clonality: Monoclonal
• Isotype: IgG3 κ
• Applications: ELISA
• Format: Purified
• Buffer: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Reconstitution: Store the TNFRSF18 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
• Limitations: This TNFRSF18 antibody is available for research use only.