GITR Antibody / TNFRSF18

• Description:

  The tumor necrosis factor receptor (TNFR) superfamily represents a growing family of type I transmembrane glycoproteins that are involved in various cellular functions, including proliferation, differentiation and programmed cell death. These proteins share homology for cysteine-rich repeats in the extracellular ligand binding domain and an intracellular death domain. Members of the TNFR superfamily transmit signals through protein-protein interactions, and these signals can lead to the activation of either the caspase and Jun kinase pathways, which promote cell death, or the NFB signaling pathway.

• UniProt:

  Q9Y5U5

• Host:

  Mouse

• Immunogen:

  Human full-length TNFRSF18 protein was used as the immunogen for this TNFRSF18 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG3 κ

• Applications:

  ELISA

• Format:

  Purified

• Buffer:

  0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

• Reconstitution:

  Store the TNFRSF18 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations:

  This TNFRSF18 antibody is available for research use only.

• CAS Number:

  9007-83-4