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Recombinant TIMP2 Antibody

CAT: 0800-V7356-20UGSize: 20 µgDry Ice: NoHazardous: No
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CAT#:0800-V7356-20UGSize:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
It recognizes a protein of 21kDa, identified as tissue inhibitor of metalloproteinases 2 (TIMP2) . It is closely related to TIMP1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP2 or gelatinase A) . It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP9 or gelatinase B) . TIMP2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
P16035
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids 56-66 (DSGNDIYGNPI) from the human protein were used as the immunogen for this recombinant TIMP2 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
TIMP2/2488R
Type
Recombinant
Applications
IHC-P
Purity
Protein A affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the recombinant TIMP2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant TIMP2 antibody is available for research use only.
Storage Conditions
Store the recombinant TIMP2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Cytoplasmic, cell surface, secreted
Image Legend
IHC staining of FFPE human placenta with recombinant TIMP2 antibody (clone TIMP2/2488R) . Required HIER: requires boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.

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