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Recombinant CD68 Antibody

CAT: 0800-V3996IHC-7MLSize: 7 mLDry Ice: NoHazardous: No
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CAT#:0800-V3996IHC-7MLSize:7 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells. [UniProt]
CAS Number
9000-83-3
Specifications
The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
UniProt
P34810
Host
Rabbit
Reactivity
Human
Immunogen
Full length recombinant human protein was used as the immunogen for the recombinant CD68 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
CDLA68-3R
Type
Recombinant
Applications
IHC-P
Purity
Protein A affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the recombinant CD68 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant CD68 antibody is available for research use only.
Storage Conditions
Store the recombinant CD68 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Location
Cytoplasmic, membrane
Image Legend
IHC staining of FFPE human tonsil with recombinant CD68 antibody (clone CDLA68-3R) . HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min followed by cooling at RT for 20 min.

UniProtKB · P34810

Macrosialin

CD68_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P34810
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CD68
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B4DVT4, Q53HR6, Q53XI3, Q96BI7
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneEndosomeLysosomeMembrane

PTM

Disulfide bondGlycoprotein

Technical term

Proteomics identificationReference proteome

Domain

RepeatSignalTransmembraneTransmembrane helix

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