CD68 Antibody

CAT: 0800-F53604-0.1MLSize: 0.1 mLDry Ice: NoHazardous: No
CAT#:0800-F53604-0.1MLSize:0.1 mL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes a 40~110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000-1:4000
UniProt
P34810
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 133-160 from the human protein was used as the immunogen for this CD68 antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
404CT9.2.5
Applications
WB, ELISA
Purity
Ascites
Format
Ascites
Buffer
In ascites with 0.09% sodium azide
Reconstitution
Aliquot the CD68 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CD68 antibody is available for research use only.
Storage Conditions
Aliquot the CD68 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In ascites with 0.09% sodium azide
Applications Notes
Titration of the CD68 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
CD68 antibody western blot analysis in WiDr lysate

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