CD68 Antibody

• Description:

  This gene encodes a 40~110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

• Specifications:

  Western blot: 1:1000-1:4000

• UniProt:

  P34810

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  A portion of amino acids 133-160 from the human protein was used as the immunogen for this CD68 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG1

• Clone:

  404CT9.2.5

• Applications:

  WB, ELISA

• Purity:

  Ascites

• Format:

  Ascites

• Buffer:

  In ascites with 0.09% sodium azide

• Reconstitution:

  Aliquot the CD68 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This CD68 antibody is available for research use only.

• Storage Conditions:

  Aliquot the CD68 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In ascites with 0.09% sodium azide

• Applications Notes:

  Titration of the CD68 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  CD68 antibody western blot analysis in WiDr lysate