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Insulin Antibody

CAT: 0800-V2636SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V2636SAF-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 0.5-1 µg/mL for 30 min at RT
UniProt
P01308
Host
Mouse
Reactivity
Human, Mouse
Immunogen
Recombinant INS protein was used as the immunogen for the Insulin antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
IRDN/805
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the Insulin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Insulin antibody is available for research use only.
Storage Conditions
Store the Insulin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Location
Cytoplasmic
Image Legend
IHC: Formalin-fixed, paraffin-embedded human pancreas stained with Insulin antibody (IRDN/805) .

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