Insulin Receptor Antibody
CAT:
800-F50643-0.2ML
Size:
0.2 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Insulin Receptor Antibody
- Description: INSR binds insulin and has a tyrosine-protein kinase activity. Autophosphorylation activates the kinase activity. This Type I mebrane protein is composed of a tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. After being transported from the endoplasmic reticulum to the Golgi apparatus, the single glycosylated precursor is further glycosylated and then cleaved, followed by its transport to the plasma membrane.
- CAS Number: 9007-83-4
- UniProt: P06213
- Host: Rabbit
- Immunogen: A portion of amino acids 21-52 from the human protein was used as the immunogen for this Insulin Receptor antibody.
- Clonality: Polyclonal
- Isotype: Ig
- Applications: IHC, WB, ELISA
- Format: Purified
- Buffer: In 1X PBS, pH 7.4, with 0.09% sodium azide
- Reconstitution: Aliquot the Insulin Receptor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
- Limitations: This Insulin Receptor antibody is available for research use only.