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Oat3 Antibody / Slc22a8

CAT: 0800-RQ6266Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6266Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Solute carrier family 22 member 8, or organic anion transporter 3 (OAT3), is a protein that in humans is encoded by the SLC22A8 gene. This gene encodes a protein involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
O88909
Host
Rabbit
Reactivity
Mouse
Immunogen
A mouse recombinant partial protein (amino acids K69-T534) was used as the immunogen for the Oat3 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, FACS, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the Oat3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Oat3 antibody is available for research use only.
Storage Conditions
After reconstitution, the Oat3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Oat3 antibody should be determined by the researcher.
Image Legend
Flow cytometry testing of human Neuro-2a cells with Oat3 antibody at 1ug/million cells (blocked with goat sera) ; Red=cells alone, Green=isotype control, Blue= Oat3 antibody.

UniProtKB · O88909

Organic anion transporter 3

S22A8_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
O88909
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Slc22a8
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
mOat3
EC number
—
Processing
—
Secondary accessions
Q3TZF9, Q8CCX3, Q8CFH5, Q91WJ9
Protein keywords

Cellular component

Cell membraneMembrane

Biological process

DetoxificationIon transportLipid transportTransport

PTM

GlycoproteinPhosphoprotein

Technical term

Reference proteome

Domain

TransmembraneTransmembrane helix

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