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SLC22A6 Antibody

CAT: 0800-R30768Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30768Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Solute carrier family 22 (organic anion transporter), member 6, also called OAT1 or PAHT, is a protein that in humans is encoded by the SLC22A6 gene, which is also a member of the organic anion transporter (OAT) family of proteins. It is a transmembrane protein that is expressed in the brain, the placenta, the eyes, smooth muscles, and the basolateral membrane of proximal tubular cells of the kidneys. It plays a central role in renal organic anion transport. Along with OAT3, OAT1/SLC22A6 mediates the uptake of a wide range of relatively small and hydrophilic organic anions from plasma into the cytoplasm of the proximal tubular cells of the kidneys. The protein functions as organic anion exchanger. When the uptake of one molecule of an organic anion is transported into a cell by an SLC22A6 exchanger, one molecule of an endogenous dicarboxylic acid (such as glutarate, ketoglutarate, etc) is simultaneously transported out of the cell.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
UniProt
Q4U2R8
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Amino acids 534-550 (QKYMVPLQASAQEKNGL-human) were used as the immunogen for this SLC22A6 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the SLC22A6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This SLC22A6 antibody is available for research use only.
Storage Conditions
After reconstitution, the SLC22A6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the SLC22A6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of SLC22A6 antibody and Lane 1: HT1080; 2: HeLa cell lysate

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