Products for Research Use Only
RegisterLogin

OCT1 Antibody / SLC22A1

CAT: 0800-R31293Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-R31293Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Solute carrier family 22 (organic cation transporter) member 1, also called OCT1 (Organic cation transporter 1) is a protein that in humans is encoded by the SLC22A1 gene. This gene is mapped to 6q25.3. Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene transports the polyamines spermine and spermidine. It also transports pramipexole across the basolateral membrane of the proximal tubular epithelial cells. This gene regulated by various intracellular signaling pathways including inhibition by protein kinase A activation, and endogenously activation by the calmodulin complex, the calmodulin-dependent kinase II and LCK tyrosine kinase.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
O15245
Host
Rabbit
Reactivity
Human
Immunogen
An amino acid sequence from the C-terminus of human SLC22A1/OCT1 (RKAKPKENTIYLKVQTSE) was used as the immunogen for this OCT1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the OCT1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This OCT1 antibody is available for research use only.
Storage Conditions
After reconstitution, the OCT1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the OCT1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of OCT1 antibody and Lane 1: human HeLa cell lysate; 2: human A549 cell lysate. Predicted molecular weight ~61 kDa but this glycoprotein may be observed at up to ~80 kDa.

UniProtKB · O15245

Solute carrier family 22 member 1

S22A1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O15245
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SLC22A1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A6NFF3, A8K1H2, C9JSU6, O15395, Q9NQD4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembrane

PTM

GlycoproteinPhosphoprotein

Biological process

Ion transportTransport

Domain

TransmembraneTransmembrane helix

Related Products

CatalogName
RQ7253Slc22a1 Antibody / Oct1
F41637-0.08MLOct1 Antibody / POU2F1
R34943-100UGOCT1 Antibody / POU2F1
F41637-0.4MLOct1 Antibody / POU2F1
R31806SLC22A2 Antibody / OCT2
R31294SLC22A3 Antibody OCT3
R35997-100UGSLC22A3 Antibody / OCT3
F54507-0.05MLSLC22A2 Antibody
R36441-100UGSLC22A16 Antibody
R30768SLC22A6 Antibody

Alternative Products

CatalogName
HY-P85303SLC22A1/OCT1 Antibody (YA4995, Rabbit)
A01945-1Anti-OCT1/Slc22a1 Antibody Picoband®
HY-P82681-01SLC22A1/OCT1 Antibody (YA2426, Rabbit)
HY-P83828-01SLC22A1/OCT1 Antibody (YA3525, Mouse)
GTR18097558OCT1/Slc22a1 Rabbit Polyclonal Antibody
MBS1755013-01Anti-OCT1/Slc22a1 Antibody Picoband
GTR18542684OCT1/Slc22a1 Rabbit Polyclonal Antibody (Biotin)
GTR18542681OCT1/Slc22a1 Rabbit Polyclonal Antibody (HRP)
GTR18542678OCT1/Slc22a1 Rabbit Polyclonal Antibody (PE)
GTR18760533OCT1/Slc22a1 Rabbit Polyclonal Antibody (Fluoro488)

Popular Products