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SLC22A8 Antibody / OAT3

CAT: 0800-RQ7661Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ7661Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Solute carrier family 22 member 8, or organic anion transporter 3 (OAT3), is a protein that in humans is encoded by the SLC22A8 gene. This gene encodes a protein involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Flow cytometry: 1-3ug/million cells, Immunofluorescence: 5 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q8TCC7
Host
Rabbit
Reactivity
Human
Immunogen
E. coli-derived recombinant human protein (amino acids M1-Q470) was used as the immunogen for the SLC22A8 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, FACS, IF, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the SLC22A8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This SLC22A8 antibody is available for research use only.
Storage Conditions
After reconstitution, the SLC22A8 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the SLC22A8 antibody should be determined by the researcher.
Image Legend
Immunofluorescent staining of FFPE human prostate cancer tissue with SLC22A8 antibody (green) and DAPI nuclear stain (blue) . HIER: steam section in pH8 EDTA buffer for 20 min.

UniProtKB · Q8TCC7

Organic anion transporter 3

S22A8_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8TCC7
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SLC22A8
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
hOAT3
EC number
—
Processing
—
Secondary accessions
B4DPH7, F5GWA8, F5H5J1, O95820, Q59EW9, Q96TC1
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembrane

Biological process

DetoxificationIon transportLipid transportTransport

PTM

GlycoproteinPhosphoprotein

Technical term

Proteomics identificationReference proteome

Domain

TransmembraneTransmembrane helix

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