Products for Research Use Only

Trem2 Antibody

CAT: 0800-RQ6214Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6214Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Triggering receptor expressed on myeloid cells 2 also known as TREM-2 is a protein that in humans is encoded by the TREM2 gene. This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL) . Alternative splicing results in multiple transcript variants encoding different isoforms.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
D3ZZ89
Host
Rabbit
Reactivity
Rat
Immunogen
A rat recombinant partial protein (amino acids L19-D131) was used as the immunogen for the Trem2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, FACS, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.0125% sodium azide
Reconstitution
After reconstitution, the Trem2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Trem2 antibody is available for research use only.
Storage Conditions
After reconstitution, the Trem2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Trem2 antibody should be determined by the researcher.
Image Legend
Flow cytometry testing of rat RH35 cells with Trem2 antibody at 1ug/million cells (blocked with goat sera) ; Red=cells alone, Green=isotype control, Blue= Trem2 antibody.
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