TREX2 Antibody

• Description:

  Three prime repair exonuclease 2 is an enzyme that in humans is encoded by the TREX2 gene. By genomic sequence analysis, the TREX2 gene is mapped to chromosome Xq28. This gene encodes a protein with 3' exonuclease activity. Enzymes with this activity are involved in DNA replication, repair, and recombination. Similarity to an E. coli protein suggests that this enzyme may be a subunit of DNA polymerase III, which does not have intrinsic exonuclease activity.

• Specifications:

  Western blot: 0.5-1 µg/mL

• UniProt:

  Q9BQ50

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Amino acids E69-A279 from the human protein were used as the immunogen for the TREX2 antibody.

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  WB

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide

• Reconstitution:

  After reconstitution, the TREX2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

• Limitations:

  This TREX2 antibody is available for research use only.

• Storage Conditions:

  After reconstitution, the TREX2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

• Formulation:

  0.5 mg/mL if reconstituted with 0.2ml sterile DI water

• Applications Notes:

  Differences in protocols and secondary/substrate sensitivity may require the TREX2 antibody to be titrated for optimal performance.

• CAS Number:

  9007-83-4

• Location:

  Nuclear

• Image Legend:

  Western blot testing of human 1) HeLa and 2) MCF7 cell lysate with TREX2 antibody at 0.5ug/ml. Predicted molecular weight ~31/26 kDa (isoforms 1/2), observed here at ~37 kDa.