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ITGB5 Antibody / Integrin beta 5

CAT: 0800-RQ5891Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ5891Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes a beta subunit of integrin, which can combine with different alpha chains to form a variety of integrin heterodimers. Integrins are integral cell-surface receptors that participate in cell adhesion as well as cell-surface mediated signaling. The alphav beta5 integrin is involved in adhesion to vitronectin.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry: 1-2 µg/mL, Immunofluorescence: 2-4 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P18084
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant human protein (amino acids S32-D689) was used as the immunogen for the ITGB5 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, FACS, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the ITGB5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This ITGB5 antibody is available for research use only.
Storage Conditions
After reconstitution, the ITGB5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the ITGB5 antibody should be determined by the researcher.
Image Legend
IHC staining of FFPE human rectal cancer with ITGB5 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

UniProtKB · P18084

Integrin beta-5

ITB5_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P18084
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ITGB5
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B0LPF8, B2RD70
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Ligand

CalciumMagnesiumMetal-binding

Biological process

Cell adhesionHost-virus interaction

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

EGF-like domainRepeatSignalTransmembraneTransmembrane helix

Molecular function

Host cell receptor for virus entryIntegrinReceptor
Product Datasheet
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