Products for Research Use Only
RegisterLogin

ITGB4 Antibody / Integrin beta 4

CAT: 0800-RQ5890Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-RQ5890Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ITGB4 (Integrin, beta-4), also known as CD104 (Cluster of Differentiation 104), is a human gene. The gene encodes the integrin beta 4 subunits, a receptor for the laminins. This subunit tends to associate with alpha 6 subunits and is likely to play a pivotal role in the biology of invasive carcinoma. The ITGB4 gene is mapped on 17q25.1. Using expression profiling, Yang et al. found that ITGB4 was upregulated 6-fold by ZKSCAN3 in transfected human colon cancer cells compared with parental cells. They confirmed that ZKSCAN3 bound the promoter of ITGB4 in vitro and in vivo. ITGB4 knockdown by short hairpin RNA countered ZKSCAN3-augmented anchorage-independent colony formation in the colon cancer cell lines. The integrin beta-4 subunit is characterized by an unusually long cytoplasmic domain that harbors 4 fibronectin type III (FNIII) repeats, residing in 2 pairs separated by a connecting segment. Vidal et al. found compound heterozygosity for mutations in the ITGB4 gene in an infant with junctional epidermolysis bullosa associated with pyloric atresia.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry: 1-2 µg/mL, Immunofluorescence: 2-4 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P16144
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant human protein (amino acids R29-K431) was used as the immunogen for the ITGB4 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, FACS, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the ITGB4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This ITGB4 antibody is available for research use only.
Storage Conditions
After reconstitution, the ITGB4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the ITGB4 antibody should be determined by the researcher.
Image Legend
Immunofluorescent staining of FFPE human intestinal cancer with ITGB4 antibody (green) and DAPI (blue) . HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

Related Products

CatalogName
R30790Integrin beta 4 Antibody / ITGB4 / CD104
V2163-20UGIntegrin Beta 4 Antibody / ITGB4 / CD104
RQ5468CD104 Antibody / Integrin beta 4 / ITGB4
V2163-100UGIntegrin Beta 4 Antibody / ITGB4 / CD104
V2163SAF-100UGIntegrin Beta 4 Antibody / ITGB4 / CD104
RQ7118Integrin beta 4 Antibody / ITGB4 / CD104
RQ8655Integrin beta 3 Antibody / ITGB3
RQ6365ITGB5 Antibody / Integrin beta 5
FY12548ITGB7 Antibody / Integrin beta 7
RQ5128CD29 Antibody / Integrin beta / ITGB1

Alternative Products

CatalogName
abx405421-01Integrin Beta-4 (ITGB4) Antibody
abx234351Integrin Beta 4 (ITGb4) Antibody
A01015-1Anti-Integrin beta ITGB4 Antibody
GTR18225326ITGB4/Integrin Beta 4 Antibody
214355Integrin beta-4 (Integrin beta 4, ITGB4, CD104)
TRV-027458-01Recombinant Integrin Beta 4 (ITGb4)
FY-AB51449-01Anti-Integrin Beta 4 (ITGB4)
TS421093P5Integrin beta 4 (ITGB4) CytoSection

Popular Products