Products for Research Use Only

Integrin beta 3 Antibody / ITGB3

CAT: 0800-RQ8655Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0800-RQ8655Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface-mediated signaling. [Wiki]
Specifications
Western blot: 1:500-1:2000
UniProt
P05106
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human Integrin beta 3 protein was used as the immunogen for the Integrin beta 3 Antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
29I49
Applications
WB
Purity
Affinity chromatography
Format
Purified
Limitations
This Integrin beta 3 antibody is available for research use only.
Storage Conditions
Store the Integrin beta 3 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the Integrin beta 3 antibody should be determined by the researcher.
Image Legend
Western blot testing of human U-87 MG cell lysate with Integrin beta 3 antibody. Predicted molecular weight ~88 kDa but may be observed at higher molecular weights due to glycosylation.

UniProtKB · P05106

Integrin beta-3

ITB3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P05106
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ITGB3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A0PJW2, D3DXJ8, O15495, Q12806, Q13413, Q14648, Q16499
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

CalciumMagnesiumMetal-binding

Biological process

Cell adhesionHost-virus interaction

Cellular component

Cell junctionCell membraneCell projectionMembranePostsynaptic cell membraneSynapse

Disease

Disease variant

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

EGF-like domainRepeatSignalTransmembraneTransmembrane helix

Molecular function

Host cell receptor for virus entryIntegrinReceptor