Bcl10 Antibody

• Description:

  Bcl10 contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. It is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. Bcl10 is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and Bcl10 are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [RefSeq]

• Specifications:

  Western blot: 1:1000-1:2000

• UniProt:

  O95999

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A synthetic peptide specific to human Bcl10 was used as the immunogen for the Bcl10 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG

• Clone:

  GDB-2

• Type:

  Recombinant

• Applications:

  WB

• Purity:

  Affinity purified

• Format:

  Purified

• Buffer:

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

• Reconstitution:

  Store the Bcl10 antibody at -20oC.

• Limitations:

  This Bcl10 antibody is available for research use only.

• Storage Conditions:

  Store the Bcl10 antibody at -20°C.

• Formulation:

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

• Applications Notes:

  Optimal dilution of the Bcl10 antibody should be determined by the researcher.

• CAS Number:

  9000-83-3

• Image Legend:

  Western blot testing of human 1) HeLa and 2) Raji cell lysate with Bcl10 antibody. Expected molecular weight: 26-33 kDa.