BCL10 antibody

• Background:

  Involved in adaptive immune response (PubMed:25365219) . Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1 (PubMed:18264101) .

• Synonyms:

  B-cell lymphoma/leukemia 10|B-cell CLL/lymphoma 10 (Bcl-10) |CARD-containing molecule enhancing NF-kappa-B|CARD-like apoptotic protein (hCLAP) |CED-3/ICH-1 prodomain homologous E10-like regulator (CIPER) |Cellular homolog of vCARMEN (cCARMEN) |Cellular-E10 (c-E10) |Mammalian CARD-containing adapter molecule E10 (mE10) |BCL10|CIPER|CLAP

• Gene ID:

  8915

• UniProt:

  O95999

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  B-cell CLL/lymphoma 10

• Target:

  BCL10

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC

• Field of Research:

  Immunology, Signal Transduction

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IHC: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  32 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC