Bcl10 Antibody

• Description :

  Bcl10 contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. It is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. Bcl10 is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and Bcl10 are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [RefSeq]

• Specifications :

  Western blot: 1:1000-1:2000

• UniProt :

  O95999

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  A synthetic peptide specific to human Bcl10 was used as the immunogen for the Bcl10 antibody.

• Clonality :

  Monoclonal

• Isotype :

  IgG

• Clone :

  GDB-2

• Type :

  Recombinant

• Applications :

  WB

• Purity :

  Affinity purified

• Format :

  Purified

• Buffer :

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

• Reconstitution :

  Store the Bcl10 antibody at -20oC.

• Limitations :

  This Bcl10 antibody is available for research use only.

• Storage Conditions :

  Store the Bcl10 antibody at -20°C.

• Formulation :

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

• Applications Notes :

  Optimal dilution of the Bcl10 antibody should be determined by the researcher.

• CAS Number :

  9000-83-3

• Image Legend :

  Western blot testing of human 1) HeLa and 2) Raji cell lysate with Bcl10 antibody. Expected molecular weight: 26-33 kDa.