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RAB6A Antibody

CAT: 0800-RQ4419Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ4419Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ras-related protein Rab-6A is a protein that in humans is encoded by the RAB6A gene located in the eleventh chromosome. This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P20340
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids RRVAAALPGMESTQDRSREDMIDIKLEKPQEQPVSE from the human protein were used as the immunogen for the RAB6A antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the RAB6A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This RAB6A antibody is available for research use only.
Storage Conditions
After reconstitution, the RAB6A antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the RAB6A antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
Western blot testing of 1) human MDA-MB-453, 2) human SK-OV-3, 3) human A431, 4) rat testis, 5) mouse brain and 6) mouse HEPA1-6 lysate with RAB6A antibody at 0.5ug/ml. Predicted molecular weight ~24 kDa.

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