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Pendrin Antibody / SLC26A4

CAT: 0800-RQ4263Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ4263Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pendrin is an anion exchange protein that in humans is encoded by the SLC26A4 gene. Pendrin is an ion exchanger found in many types of cells in the body. High levels of pendrin expression have been identified in the inner ear and thyroid. In the thyroid, pendrin mediates a component of the efflux of iodide across the apical membrane of the thyrocyte, which is critical for the formation of thyroid hormone. The exact function of pendrin in the inner ear remains unclear; however, pendrin may play a role in acid-base balance as a chloride-bicarbonate exchanger, regulate volume homeostasis through its ability to function as a chloride-formate exchanger or indirectly modulate the calcium concentration of the endolymph.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
O43511
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids RSLRVIVKEFQRIDVNVYFASLQDYVIEKLEQ were used as the immunogen for the Pendrin antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the Pendrin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Pendrin antibody is available for research use only.
Storage Conditions
After reconstitution, the Pendrin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Pendrin antibody should be determined by the researcher.
Location
Membrane
Image Legend
Western blot testing of human 1) HK-2 and 2) 293T cell lysate with Pendrin antibody at 0.5ug/ml. Predicted molecular weight ~86 kDa.

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