Reveromycin D

CAT: 0804-HY-W747507Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-W747507Size:1 Each
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Description
Reveromycin D is a bacterial metabolite originally isolated from Streptomyces. It inhibits EGF-induced mitogenic activity in Balb/MK cells and has pH-dependent antifungal activity against C. albicans (MICs=2 and >500 μg/mL at pH 3 and 7.4, respectively) .2 Reveromycin D also inhibits proliferation of KB and K562 cells (IC50s=1.6 and 1.3 μg/mL, respectively) .
CAS Number
[144860-70-8]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/reveromycin-d.html
Smiles
CCCCC[C@@]1(C[C@@H](O[C@@]2(C1)CC[C@@H]([C@H](O2)C/C=C(\C)/C=C/[C@@H]([C@@H](C)/C=C/C(=O)O)O)C)/C=C/C(=C/C(=O)O)/C)OC(=O)CCC(=O)O
Molecular Formula
C37H54O11
Molecular Weight
674.82
References & Citations
[1]Takahashi, et al. Reveromycins, new inhibitors of eukaryotic cell growth. II. Biological activities. J. Antibiot. (Tokyo) 45 (9), 1414-1419 (1992) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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