TIMP3 Antibody

CAT: 0800-R32078Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-R32078Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Metalloproteinase inhibitor 3 is a protein that in humans is encoded by the TIMP3 gene. It is mapped to 22q12.1-q13.2. This gene belongs to the tissue inhibitor of metalloproteinases gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of theextracellular matrix (ECM) . Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL, ELISA: 0.1-0.5 µg/mL (human protein tested) ; request BSA-free format for coating
UniProt
P35625
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids 24-211 of human TIMP3 were used as the immunogen for the TIMP3 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, ELISA (protein)
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the TIMP3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This TIMP3 antibody is available for research use only.
Storage Conditions
After reconstitution, the TIMP3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the TIMP3 antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) rat kidney, 2) mouse ovary, 3) human HeLa, 4) human MCF7 and 5) human SMMC lysate with TIMP3 antibody. Expected/observed molecular weight: ~24/33 kDa (unmodified/glycosylated) .

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