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TIMP4 Antibody

CAT: 0800-R32783Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32783Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Metalloproteinase inhibitor 4 is an enzyme that in humans is encoded by the TIMP4 gene. And this gene is mapped to chromosome 3p25. This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL, Flow cytometry: 1-3ug/10^6 cells, Immunofluorescence (FFPE) : 2-4 µg/mL, ELISA: 0.1-0.5 µg/mL (human protein tested; request BSA-free format for coating)
UniProt
Q99727
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids N174-P224 from the human protein were used as the immunogen for the TIMP4 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, FACS, IF, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
Reconstitution
After reconstitution, the TIMP4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This TIMP4 antibody is available for research use only.
Storage Conditions
After reconstitution, the TIMP4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the TIMP4 antibody should be determined by the researcher.
Location
Secreted
Image Legend
IHC testing of FFPE human lung cancer tissue with TIMP4 antibody at 1ug/ml. Required HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to testing.

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