TIMP1 Antibody

• Description:

  This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [RefSeq]

• Specifications:

  Western blot: 1:500-1:2000

• UniProt:

  P01033

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A synthetic peptide specific to human TIMP1 was used as the immunogen for the TIMP1 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG

• Clone:

  AAOD-20

• Type:

  Recombinant

• Applications:

  WB

• Purity:

  Affinity purified

• Format:

  Purified

• Buffer:

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

• Reconstitution:

  Store the TIMP1 antibody at -20oC.

• Limitations:

  This TIMP1 antibody is available for research use only.

• Storage Conditions:

  Store the TIMP1 antibody at -20°C.

• Formulation:

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

• Applications Notes:

  Optimal dilution of the TIMP1 antibody should be determined by the researcher.

• CAS Number:

  9000-83-3

• Image Legend:

  Western blot testing of human prostate cancer lysate with TIMP1 antibody. Expected molecular weight: 23-28 kDa depending on the level of glycosylation.