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SIRT6 Antibody

CAT: 0800-R31770Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31770Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sirtuin 6, also known as SIR2L6, is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT6 is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Human partial recombinant protein (AA 14-180) was used as the immunogen for this SIRT6 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the SIRT6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This SIRT6 antibody is available for research use only.
Storage Conditions
After reconstitution, the SIRT6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting points. Titration of the SIRT6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of SIRT6 antibody and Lane 1: HeLa; 2: A549; 3: human placenta lysate

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