Products for Research Use Only
RegisterLogin

SIRT7 Antibody

CAT: 0800-F49523-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-F49523-0.08MLSize:0.08 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SIRT7 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:50-1:100
UniProt
Q9NRC8
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 331-360 from the human protein was used as the immunogen for this SIRT7 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the SIRT7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SIRT7 antibody is available for research use only.
Storage Conditions
Aliquot the SIRT7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the SIRT7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Mouse, Rat, Bovine
Image Legend
Western blot analysis of SIRT7 antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SIRT7 gene (2) .

UniProtKB · Q9NRC8

NAD-dependent protein deacetylase sirtuin-7

SIR7_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NRC8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SIRT7
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.3.1.286
Processing
—
Secondary accessions
A8K2K0, B3KSU8, Q3MIK4, Q9NSZ6, Q9NUS6
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Molecular function

Chromatin regulatorHydrolaseRepressorTransferase

Cellular component

ChromosomeCytoplasmNucleus

Biological process

DNA damageDNA repairTranscriptionTranscription regulation

Ligand

Metal-bindingNADZinc

PTM

MethylationPhosphoproteinUbl conjugation

Related Products

CatalogName
F43965-0.4MLSIRT3 Antibody
F53070-0.4MLSirt1 Antibody
F49519-0.4MLSIRT3 Antibody
F43446-0.4MLSIRT6 Antibody
F53070-0.08MLSirt1 Antibody
F52857-0.08MLSIRT1 Antibody
F43446-0.08MLSIRT6 Antibody
V9647-20UGSIRT1 Antibody
F43966-0.4MLSIRT5 Antibody
F52857-0.4MLSIRT1 Antibody

Alternative Products

CatalogName
70R-11612SIRT7 antibody

Popular Products