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TLR1 Antibody

CAT: 0800-R31370Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31370Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Toll-like receptor 1 (TLR1), also called TIL or CD281 is a member of the Toll-like receptor family (TLR) of pattern recognition receptors of the innate immune system. This gene is mapped to 4p14 by fluorescence in situ hybridization. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
Q15399
Host
Rabbit
Reactivity
Human
Immunogen
An amino acid sequence from the C-terminus of human TLR1 (NLRAAINIKLTEQAKK) was used as the immunogen for this TLR1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the TLR1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This TLR1 antibody is available for research use only.
Storage Conditions
After reconstitution, the TLR1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting points. Titration of the TLR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of TLR1 antibody and Lane 1: COLO320; 2: SW620; 3: SKOV; 4: Jurkat; 5: CEM; 6: PANC lysate. Predicted molecular weight ~90 kDa.
Product Datasheet
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