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IRAK2 Antibody

CAT: 0800-R31360Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31360Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Interleukin-1 receptor-associated kinase-like 2 is an enzyme that in humans is encoded by the IRAK2 gene. This gene is mapped to 3p25.3. Interleukin-1 receptor-associated kinase 2 is one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB. It binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL, Immunocytochemistry: 0.5-1 µg/mL
UniProt
O43187
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
An amino acid sequence from the C-terminus of human IRAK2 (EAKRKLMENILLYKEEK) was used as the immunogen for this IRAK2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC-P, ICC
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the IRAK2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This IRAK2 antibody is available for research use only.
Storage Conditions
After reconstitution, the IRAK2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting points. Titration of the IRAK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of IRAK2 antibody and Lane 1: 22RV; 2: A549; 3: PANC; 4: SMMC-7721 cell lysate
Product Datasheet
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