Products for Research Use Only
RegisterLogin

IRAK1 Antibody

CAT: 0800-F50783-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-F50783-0.08MLSize:0.08 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine-like kinase (TLK) group consists of 40 tyrosine and serine-threonine kinases such as MLK (mixed-lineage kinase), LISK (LIMK/TESK), IRAK (interleukin-1 receptor-associated kinase), Raf, RIPK (receptor-interacting protein kinase), and STRK (activin and TGF-beta receptors) families.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:10-1:100
UniProt
P51617
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 683-712 from human IRAK1 was used as the immunogen for this IRAK antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the IRAK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This IRAK antibody is available for research use only.
Storage Conditions
Aliquot the IRAK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the IRAK antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot analysis of IRAK antibody and 293 cell lysate either nontransfected (Lane 1) or transiently transfected with the IRAK1 gene (2) . Predicted molecular weight 68-76 kDa.

UniProtKB · P51617

Interleukin-1 receptor-associated kinase 1

IRAK1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P51617
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IRAK1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IRAK-1
EC number
2.7.11.1
Processing
—
Secondary accessions
D3DWW3, D3DWW4, Q7Z5V4, Q96C06, Q96RL2
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingMagnesiumNucleotide-binding

Cellular component

CytoplasmLipid dropletNucleus

Biological process

Host-virus interactionImmunityInnate immunity

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Molecular function

KinaseSerine/threonine-protein kinaseTransferase
Product Datasheet
Loading...

Related Products

CatalogName
F50786-0.08MLIRAK3 Antibody / IRAKM
F50786-0.4MLIRAK3 Antibody / IRAKM
F43676-0.4MLIrak3 Antibody
F43676-0.08MLIrak3 Antibody
R31330IRAKM Antibody
F50784-0.4MLIRAK2 Antibody
R34098-100UGIRAK3 Antibody
F42537-0.4MLIRAK4 Antibody
F43563-0.08MLIrak4 Antibody
F50785-0.08MLIRAK2 Antibody

Alternative Products

CatalogName
70R-49924IRAK1 antibody

Popular Products