RIP2 Antibody

CAT: 0800-R30960Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-R30960Size:100 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Receptor-interacting serine/threonine-protein kinase 2, also known as CARD3, CARDIAK, RICK, and RIP2, is an enzyme that in humans is encoded by the RIPK2 gene. It has 540-amino acid protein in length. Northern blot analysis revealed that RIPK2 is expressed in various human tissues as 2.5- and 1.8-kb mRNAs that differ due to alternative polyadenylation. It is a novel kinase that may regulate apoptosis induced by the FAS receptor pathway. This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminalcaspase recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappa Band inducer of apoptosis in response to various stimuli, CARDIAK (CARD-containing ICE-associated kinase) specifically interacted with the CARD of ICE/caspase-1, and this interaction correlated with the processing of pro-caspase-1 and the formation of the active caspase-1 p20 subunit.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
O43353
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
An amino acid sequence from the C-terminus of human RIP2 (DIQGEEFAKVIVQKLKDNKQ) was used as the immunogen for this RIP2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the RIP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This RIP2 antibody is available for research use only.
Storage Conditions
After reconstitution, the RIP2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the RIP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of RIP2 antibody and Lane 1: A549; 2: HeLa; 3: PANC; 4: COLO320 cell lysate. Predicted molecular weight: ~61 kDa.

Related Products

CatalogName
F43229-0.4MLRIPK2 Antibody
F50800-0.08MLRIPK2 Antibody
R31366RIP3 Antibody
F50800-0.4MLRIPK2 Antibody
F43229-0.08MLRIPK2 Antibody
R31540RIP1 Antibody / RIPK1
RQ8197RUFY3 Antibody / RIPx
R31162RIP Antibody / RIPK1
FY13346Phospho-RIP3 (Ser232) Antibody / RIPK3
FY13052RIPK2 Antibody / Receptor interacting serine threonine kinase 2

Alternative Products

CatalogName
B8180-01RIP2 Antibody
BS65635RIP2 Polyclonal Antibody
STJ95512Anti-RIP2 antibody
bsm-62783R-01RIP2 Recombinant Antibody
RC-16567-01Recombinant RIP2 Antibody
SL34105R-01Rabbit Anti-RIP2 antibody
MF-0088022-01Anti-RIP2 Antibody (7Y296)
APRab17207-01RIP2 Rabbit Polyclonal Antibody
A8180-01RIP2 (phospho Ser176) Antibody
BS41473-01RIP2 Rabbit monoclonal antibody

Popular Products