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LAMP1 Antibody / CD107A

CAT: 0800-R30920Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30920Size:100 µg
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Description
Lysosomal-associated membrane protein 1, also called LAMPA, LGP120 or CD107A, is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. It has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells. By means of in situ hybridization, Mattei et al. (1990) assigned the gene to chromosome 13q34. Hybridization of LAMP1 cDNA to chromosome 12p13.3 was observed even when probes representing different portions of the LAMP1cDNA were used.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P11279
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Amino acids 403-417 (YLVGRKRSHAGYQTI) were used as the immunogen for this LAMP1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the LAMP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This LAMP1 antibody is available for research use only.
Storage Conditions
After reconstitution, the LAMP1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting points. Titration of the LAMP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of 1) human HepG2, 2) human Jurkat, 3) human HeLa, 4) mouse brain and 5) mouse lung tissue lysate with LAMP1 antibody. This heavily glycosylated protein of 417 amino acids can be visualized at up to 140 kDa.

UniProtKB · P11279

Lysosome-associated membrane glycoprotein 1

LAMP1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P11279
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LAMP1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
LAMP-1, Lysosome-associated membrane protein 1
EC number
—
Processing
Precursor
Secondary accessions
B4DWL3, Q8WU33, Q96I40, Q9BRD2, Q9NP13
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneEndosomeLysosomeMembrane

PTM

Disulfide bondGlycoprotein

Molecular function

Host cell receptor for virus entryReceptor

Biological process

Host-virus interaction

Domain

SignalTransmembraneTransmembrane helix
Product Datasheet
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