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CD107b Antibody / LAMP2

CAT: 0800-RQ7090Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ7090Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lysosome-associated membrane protein 2 (LAMP2), also known as CD107b (Cluster of Differentiation 107b) and Mac-3, is a human gene. Its protein, LAMP2, is one of the lysosome-associated membrane glycoproteins. The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P13473
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human protein (amino acids D128-F410) was used as the immunogen for the CD107b antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the CD107b antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This CD107b antibody is available for research use only.
Storage Conditions
After reconstitution, the CD107b antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the CD107b antibody should be determined by the researcher.
Image Legend
Western blot testing of human 1) U-87 MG, 2) PC-3, 3) 293T, 4) Jurkat, 5) HepG2 and 6) HeLa cell lysate with CD107b antibody. The protein can be extensively glycosylated and visualized from 45~110 kDa.

UniProtKB · P13473

Lysosome-associated membrane glycoprotein 2

LAMP2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P13473
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LAMP2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
LAMP-2, Lysosome-associated membrane protein 2
EC number
—
Processing
Precursor
Secondary accessions
A8K4X5, D3DTF0, Q16641, Q6Q3G8, Q96J30, Q99534, Q9UD93
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Autophagy

Cellular component

Cell membraneCytoplasmic vesicleEndosomeLysosomeMembrane

Disease

Disease variantGlycogen storage disease

PTM

Disulfide bondGlycoprotein

Domain

SignalTransmembraneTransmembrane helix

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