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MMP9 Antibody

CAT: 0800-R30424Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30424Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Matrix metallopeptidase 9 (MMP-9), also known as 92 kDa type IV collagenase, 92 kDa gelatinase or gelatinase B (GELB), is an enzyme that in humans is encoded by the MMP9 gene. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P14780
Host
Rabbit
Reactivity
Human
Immunogen
An amino acid sequence from the C-terminus of human MMP9 (NQVDQVGYVTYDILQCP) was used as the immunogen for this MMP9 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the MMP9 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This MMP9 antibody is available for research use only.
Storage Conditions
After reconstitution, the MMP9 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the MMP9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic, nuclear, secreted
Image Legend
Western blot testing of MMP9 antibody and Lane 1: rat embryo; 2: MM453; 3: HeLa; 4: SMMC-7721; 5: Jurkat; 6: HT1080. Predicted molecular weight: 92/67-80 kDa (precursor/mature forms) .
Product Datasheet
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