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Rat Il10 Antibody

CAT: 0800-R30118Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30118Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Interleukin-10 is an anti-inflammatory cytokine. In humans IL-10 is encoded by the IL10 gene. It is capable of inhibiting synthesis of pro-inflammatory cytokines like IFN-gamma, IL-2, IL-3, TNFalpha and GM-CSF made by cells such as macrophages and regulatory T-cells. IL-10 also displays potent abilities to suppress the antigen presentation capacity of antigen presenting cells.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, ELISA: 0.1-0.5 µg/mL (rat protein tested)
UniProt
P29456
Host
Rabbit
Reactivity
Rat
Immunogen
Rat partial recombinant protein (AA 19-178) was used as the immunogen for this Il10 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, ELISA (protein)
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the Il10 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Il10 antibody is available for research use only.
Storage Conditions
After reconstitution, the Il10 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Variations in secondary/substrate sensitivities and test protocols may require the Il10 antibody to be titrated for optimal performance.
Image Legend
IHC staining of FFPE rat spleen tissue with Il10 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

UniProtKB · P29456

Interleukin-10

IL10_RAT · Rattus norvegicus

View on UniProt ↗
Primary accession
P29456
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Il10
Protein existence
2: Evidence at transcript level
Organism
Rattus norvegicus (Rat)
Taxonomy ID
10116
Alternative names
IL-10
EC number
—
Processing
Precursor
Secondary accessions
Q63263
Protein keywords

Molecular function

Cytokine

PTM

Disulfide bondGlycoprotein

Technical term

Reference proteome

Cellular component

Secreted

Domain

Signal
Product Datasheet
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