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Map3k7 Antibody / Tak1

CAT: 0800-F54678-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F54678-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1:25, Western blot: 1:500-1:2000
UniProt
Q62073
Host
Rabbit
Reactivity
Mouse
Immunogen
A portion of amino acids 131-160 from the mouse protein was used as the immunogen for the Map3k7 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC-P, WB
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Map3k7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Map3k7 antibody is available for research use only.
Storage Conditions
Aliquot the Map3k7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the Map3k7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic, plasma membrane
Image Legend
IHC testing of FFPE mouse stomach tissue with Map3k7 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
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