Products for Research Use Only
RegisterLogin

TAK1 Antibody / MAP3K7

CAT: 0800-RQ4734Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-RQ4734Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
The protein encoded by the MAP3K7 gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses.
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000, Immunofluorescence/Immunocytochemistry: 1:100-1:500
UniProt
O43318
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthetic peptide specific to human MAP3K7/TAK1 was used as the immunogen for the TAK1 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
ACHF-13
Type
Recombinant
Applications
IF/ICC, WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the TAK1 antibody at -20oC.
Limitations
This TAK1 antibody is available for research use only.
Storage Conditions
Store the TAK1 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the TAK1 antibody should be determined by the researcher.
Image Legend
Western blot testing of human HeLa cell lysate with TAK1 antibody. Predicted molecular weight: 64-69 kDa, routinely observed at 78-82 kDa.

UniProtKB · O43318

Mitogen-activated protein kinase kinase kinase 7

M3K7_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O43318
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MAP3K7
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.25
Processing
—
Secondary accessions
B2RE27, E1P523, O43317, O43319, Q5TDN2, Q5TDN3, Q5TDT7, Q9NTR3, Q9NZ70
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisHost-virus interactionStress responseTranscriptionTranscription regulation

Ligand

ATP-bindingMagnesiumMetal-bindingNucleotide-binding

Cellular component

Cell membraneCytoplasmMembrane

Disease

Disease variant

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

Related Products

CatalogName
F54678-0.4MLMap3k7 Antibody / Tak1
F54678-0.08MLMap3k7 Antibody / Tak1
F54074-0.05MLPhospho-TAK1 Antibody (Ser439)
RQ7779TAB1 Antibody / TAK1-binding protein 1 / MAP3K7IP1
V2702-100UGMAP3K1 Antibody
R32444MAP3K8 Antibody
R35532-100UGMAP3K6 Antibody
V2702-20UGMAP3K1 Antibody
V2702SAF-100UGMAP3K1 Antibody
V2702IHC-7MLMAP3K1 Antibody

Alternative Products

CatalogName
GTR17697003TAK1/MAP3K7 Antibody
STJ70932Anti-TAK1 / MAP3K7 antibody
bsm-54071RTAK1/MAP3K7 Recombinant Antibody
TA378276TAK1 (MAP3K7) Rabbit Polyclonal Antibody
SL20530R-01Rabbit Anti-TAK1/MAP3K7 antibody
GTR17764799-01TAK1/MAP3K7 Rabbit Polyclonal Antibody
TA423239TAK1 (MAP3K7) Rabbit Monoclonal Antibody
TA303111TAK1 (MAP3K7) Goat Polyclonal Antibody
PB10006Anti-TAK1/MAP3K7 Antibody Picoband®
dAP-0859Goat anti-TAK1 / MAP3K7 Antibody

Popular Products